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 Clinical Research

Clinical Research Trials

Research Studies for Dermatologic Conditions

Advanced Dermatology and Cosmetic Surgery is a multi-state dermatology practice with more than 155 locations nationwide. The Clinical Research Division was founded to find new and better ways to treat patients with dermatologic conditions through FDA-supervised clinical trials of leading-edge drugs, devices and other treatments.

Psoriasis Online Research Study

Ages 18 and up. Qualifying patients will have a diagnosis of psoriasis and must be able to speak fluently in English and must be under the care of an Advanced Dermatology and Cosmetic Surgery (or any other member of the Advanced Dermatology brand family) provider. 

Psoriasis is a chronic inflammatory skin condition that affects 2-3% of US adults. Psoriasis has a significant impact on patients’ lives, even when mild. It can be itchy or painful and in severe cases can crack and bleed.  

Study Overview

To enroll, click here to provide consent and sign up.


 

Study Details

In partnership with the Arthritis Research Foundation, Advanced Dermatology and Cosmetic Surgery is requesting participation of patients who have been diagnosed with Psoriasis in this registry. The primary objective of this study is to identify risk factors for the development of cardiovascular disease, diabetes, and PsA among patients with psoriasis.  There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist.

Compensation: up to $200
Duration: 2 Years
Visits: none, participants will complete 4 questionnaires online during the 2 year period
Sex: Male or Female

Studies at Warren, Michigan

Grekin Skin Institute-Warren
​13450 E. 12 Mile Road
Warren, MI 48088

The following clinical trials, under the direction of Dr. Steven Grekin, are open and requesting participants who live in or near Warren or can travel here. Dr. Grekin, founder of The Grekin Skin Institute, has been involved in Clinical Research for drug and device development since 2002. He continues a family legacy of providing extraordinary dermatologic care and treatment which dates back through more than 100 years of physicians, including seven dermatologists.


 

Vitiligo (loss of skin color)

Ages 18 - 75.  Qualifying patients will have Vitiligo.

Vitiligo is a chronic autoimmune disorder that causes patches of skin to lose pigment or color.  This happens when melanocytes, the skin cells that make pigment, are attacked and destroyed, causing the skin to lose color.    


 

Study Details

Grekin Skin Institute is enrolling adults for the RECELL® Autologous Cell Harvesting Device for the treatment of certain cases of vitiligo. The study will last 24 weeks. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $750 compensation for time and travel.

Compensation: up to $750
Duration: 24 weeks
Visits: 6
Sex: Male or Female

 

Alopecia Areata (AA, patchy hair loss, or spot baldness)

Ages 18 - 75.  Qualifying patients will have severe Alopecia Areata.

Alopecia Areata, also known as AA, patchy hair loss, or spot baldness, is an autoimmune disease that occurs when the immune system attacks hair follicles with the main symptom presenting as hair loss.  


 

Study Details

Grekin Skin Institute is enrolling adults for a Phase 2a, randomized, double-blind, placebo-controlled, proof-of-concept trial of ADX-914 for the treatment of severe Alopecia Areata study.

The purpose is to evaluate how effective injections of the investigational drug called ADX-914 is on reducing hair loss in patients with severe alopecia areata. The study consists of receiving an injection under the skin of either the investigational product ADX-914 or placebo every 2 weeks over a 24-week period. You will be randomly assigned to receive the study drug or placebo. You have 3:1 chance (75%) of receiving the investigational product. 

There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $1,700 compensation for time and travel.

Compensation: $100 per visit, up to $1,700
Duration: 36 weeks
Visits: up to 17
Sex: Male or Female

 

Atopic Dermatitis (Eczema)

Ages 18 - 75.  Qualifying patients will have moderate to severe atopic dermatitis (eczema). 

Atopic dermatitis, also known as eczema, is a chronic, inflammatory skin condition that's common in young children, but can occur at any age. It may cause itchiness, dry skin, rashes, scaly patches, thickening of the skin, blisters, and skin infections. This condition can weaken your skin’s barrier function, which helps your skin retain moisture and protects your body from outside elements. While there is no cure for eczema, dermatologists specialize in managing its symptoms through various treatments.


 

Study Details

Grekin Skin Institute is enrolling adults for an Efficacy and Safety Study of RPTI93 in Adults with Moderate to Severe Atopic Dermatitis. The study will last 6 months. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $750 compensation for time and travel.

Compensation: $75 per visit, up to $750
Duration: 6 months
Visits: 10
Sex: Male or Female

 

Atopic Dermatitis (Eczema)

Ages 18 and up.  Qualifying patients will have moderate to severe atopic dermatitis (eczema). 

Atopic dermatitis, also known as eczema, is a chronic, inflammatory skin condition that's common in young children, but can occur at any age. It may cause itchiness, dry skin, rashes, scaly patches, thickening of the skin, blisters, and skin infections. This condition can weaken your skin’s barrier function, which helps your skin retain moisture and protects your body from outside elements. While there is no cure for eczema, dermatologists specialize in managing its symptoms through various treatments.


 

Study Details

Grekin Skin Institute is enrolling adults for a double-blind, randomized, placebo treatment controlled study. The study will last 16 weeks with an 8-week follow up. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $1,300 compensation for time and travel.

Compensation: $1,300
Duration: 24 Weeks
Visits: 10
Sex: Male or Female

 

Psoriasis

Ages 18 and up. Qualifying patients will have moderate to severe plaque psoriasis. 

Plaque psoriasis is the most common type and is characterized by dry, red and raised lesions (called plaques) that are covered with silvery white buildup of dead skin cells. The itchy and sometimes painful plaques often form on the scalp, elbows, knees and lower back, though they can appear anywhere on the body. When something causes psoriasis to flare-up, skin cells grow abnormally fast ­– in just days instead of weeks. The result is a buildup of cells and thick patches of red skin with silvery scales that can flake off like dandruff. 


 

Study Details

Grekin Skin Institute is enrolling adults for a Phase 3, Randomized, Multicenter, Double-Blind, Placebo- and Active Comparator-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis. The study will last for up to 1 year. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $2,025 compensation for time and travel.

Compensation: $2,025
Duration: 56 Weeks
Visits: 18
Sex: Male or Female

Psoriasis

Ages 18 - 75. Qualifying patients will have moderate to severe plaque psoriasis. 

Plaque psoriasis is the most common type and is characterized by dry, red and raised lesions (called plaques) that are covered with silvery white buildup of dead skin cells. The itchy and sometimes painful plaques often form on the scalp, elbows, knees and lower back, though they can appear anywhere on the body. When something causes psoriasis to flare-up, skin cells grow abnormally fast ­– in just days instead of weeks. The result is a buildup of cells and thick patches of red skin with silvery scales that can flake off like dandruff. 


 

Study Details

Grekin Skin Institute is enrolling adults for a Phase 2, multicenter, randomized, double blinded, parallel dose group, placebo controlled, dose-ranging study to evaluate the efficacy and safety of 3 doses of TLL018. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $1,000 compensation for time and travel.

Compensation: $1,000
Duration: 24 Weeks
Visits: 10
Sex: Male or Female

Psoriasis

Ages 18 - 75. Qualifying patients will have a clinical diagnosis of plaque psoriasis for at least six months. 

Plaque psoriasis is the most common type and is characterized by dry, red and raised lesions (called plaques) that are covered with silvery white buildup of dead skin cells. The itchy and sometimes painful plaques often form on the scalp, elbows, knees and lower back, though they can appear anywhere on the body. When something causes psoriasis to flare-up, skin cells grow abnormally fast ­– in just days instead of weeks. The result is a buildup of cells and thick patches of red skin with silvery scales that can flake off like dandruff. 


 

Study Details

Grekin Skin Institute is conducting a study comparing an investigational topical medication (generic) to an approved (marketed) topical medication. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $150 compensation for time and travel.

Compensation: Up to $150
Duration: Eight Weeks
Visits: Three In-Office Visits
Sex: Male or Female

Studies at Spartanburg, South Carolina - Coming Soon

Advanced Dermatology and Cosmetic Surgery
1650 Skylyn Dr, Ste 402
Spartanburg, SC 29307

 

Join Clinical Trials

To learn more about our clinical trials or to participate in current or future trials, please complete the form.

Acceptance in our clinical trials may sometimes require travel to the research facility to participate. Are you willing to travel?*

In the News

In the past, our clinical study results indicated that more than one million skin cancers went undiagnosed in 2020 as a result of COVID-19 concerns, and that total-body skin cancer exams are the most effective way to find skin cancers were published nationally in the January 19, 2021 edition of the Journal of the American Academy of Dermatology (JAAD) and Journal of Clinical Oncology®, an American Society of Clinical Oncology (ASCO) Journal.

 

About Us

What We Do, Our Mission, and Research Investigators

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Sponsors and CROs

Reasons to Partner With Us on Clinical Trials

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Locations

Advanced Dermatology and
Cosmetic Surgery
725 W Granada Blvd, Ste 44
Ormond Beach, FL 32174
 

Grekin Skin Institute
Part of Advanced Dermatology and Cosmetic Surgery
13450 E. 12 Mile Rd.
Warren, Michigan 48088

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