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Clinical Research Trials

Research Studies for Dermatologic Conditions

Advanced Dermatology and Cosmetic Surgery is a multi-state dermatology practice with more than 155 locations nationwide. The Clinical Research Division was founded to find new and better ways to treat patients with dermatologic conditions through FDA-supervised clinical trials of leading-edge drugs, devices and other treatments.

Melanoma Chart Review Study

Males and Females, Ages 18 - 90.  Qualifying patients have or have had melanoma skin cancer.

Melanoma skin cancer is a type of skin cancer originating from melanocytes, the cells that produce pigment. The Decision DX Melanoma diagnostic test is used to assess the risk of metastasis and recurrence in patients with melanoma by analyzing the tumor's genetic profile.    

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Study Details

Participating patients must be diagnosed with Melanoma skin cancer with a Decision DX melanoma diagnostic test. This is a Melanoma chart review study, a research method involving the analysis of medical records (charts) of patients diagnosed with melanoma. The goal is to gather and evaluate data on patient demographics, treatment outcomes, disease progression, and other relevant clinical information to draw conclusions about the effectiveness of treatments, patient prognoses, or trends in melanoma care.

Compensation: TBD
Duration: 10 year study, chart review every 6 months
Visits: none

 

Research Studies at Warren, Michigan

Grekin Skin Institute-Warren
​13450 E. 12 Mile Road
Warren, MI 48088

The following clinical trials, under the direction of Dr. Steven Grekin, are open and requesting participants who live in or near Warren or can travel here. Dr. Grekin, founder of The Grekin Skin Institute, has been involved in Clinical Research for drug and device development since 2002. He continues a family legacy of providing extraordinary dermatologic care and treatment which dates back through more than 100 years of physicians, including seven dermatologists.

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Nasolabial Fold Dermal Filler Study

Males and Females, Ages 22+.  Qualifying patients will have moderate to severe nasolabial folds (crease from the bottom of the nostril area to the corner of the mouth).

 

Study Details

A prospective, multi-center, randomized, controlled, double-blind, split-face study of the safety and effectiveness of a new dermal filler in the treatment of nasolabial folds.

Compensation: up to $850
Duration: 100 weeks
Visits: 16

 

Chronic Urticaria (Itch)

Males and Females, Ages 18+.  Qualifying patients will have Chronic Urticaria.

Chronic urticaria is a condition characterized by the presence of hives, or wheals, on the skin that last for more than six weeks, often accompanied by itching and swelling. 

 

Study Details

A Phase 3 randomized, double-blind, placebo-controlled study to assess the efficacy and safety of Barzolvolimab in patients with Chronic Spontaneous Urticaria who remain symptomatic despite H1 Antihistamine Treatment.

Compensation: up to $1,600
Duration: 68 weeks
Visits: 19

 

Hidradenitis Suppurativa (Acne Inversa)

Males and Females, Ages 18+.  Qualifying patients will have moderate to severe Hidradenitis Suppurativa.

Hidradenitis suppurativa is a chronic inflammatory skin condition characterized by painful, swollen lumps that can rupture and cause abscesses, often occurring in areas where skin rubs together, such as the armpits, groin, and under the breasts. 

 

Study Details

A study to evaluate the efficacy and safety of subcutaneous sonelokimab compared with placebo in adult participants with moderate to severe Hidradenitis Suppurativa.  Subcutaneous sonelokimab is a type of monoclonal antibody administered via injection under the skin, designed to target and inhibit specific proteins involved in an inflammatory response.

Compensation: up to $1,400
Duration: 56 weeks
Visits: 20

 

Atopic Dermatitis (Eczema)

Males and Females, Ages 18 and up.  Qualifying patients will have moderate to severe atopic dermatitis (eczema). 

Atopic dermatitis, also known as eczema, is a chronic, inflammatory skin condition that's common in young children, but can occur at any age. It may cause itchiness, dry skin, rashes, scaly patches, thickening of the skin, blisters, and skin infections. This condition can weaken your skin’s barrier function, which helps your skin retain moisture and protects your body from outside elements. While there is no cure for eczema, dermatologists specialize in managing its symptoms through various treatments.

 

Study Details

Grekin Skin Institute is enrolling adults for a double-blind, randomized, placebo treatment controlled study. The study will last 16 weeks with an 8-week follow up. There is no cost to participate, and insurance is not required. Qualified participants will be under the supervision of a board-certified dermatologist and receive up to $1,300 compensation for time and travel.

Compensation: $1,300
Duration: 24 Weeks
Visits: 10

 

Research Studies at Spartanburg, South Carolina

Advanced Dermatology and Cosmetic Surgery
1650 Skylyn Dr, Ste 402
Spartanburg, SC 29307

Submit Your Interest

 

Hidradenitis Suppurativa (Acne Inversa)

Males and Females, Ages 16+.  Qualifying patients will have moderate to severe Hidradenitis Suppurativa.

Hidradenitis suppurativa is a chronic inflammatory skin condition characterized by painful, swollen lumps that can rupture and cause abscesses, often occurring in areas where skin rubs together, such as the armpits, groin, and under the breasts. 

 

Study Details

The INTREPID HS Study is a year-long clinical trial that aims to evaluate the safety and effectiveness of an investigational drug compared to a placebo in reducing symptoms and improving the quality of life for people with HS. Eligible participants will randomly receive either the investigational drug or a placebo for 16 weeks through weekly subcutaneous injections. After 16 weeks, all participants will receive the investigational drug, either weekly or every other week. The study involves around 18 visits, and those who complete it may have the option to join a long-term extension study to continue receiving the investigational drug. Visit Hidradenitis Suppurativa Clinical Research Study online or contact the study team to learn more.

Compensation: up to $2,400
Duration: 52 weeks
Visits: 32

 

Atopic Dermatitis (Eczema)

Males and Females, Ages 18 - 64.  Qualifying patients will have moderate to severe atopic dermatitis (eczema) diagnosed at least 3 years ago. 

AD is a chronic skin condition that can cause dry, itchy patches, discoloration of the skin, and inflammation. The SWITCH-UP Study is evaluating an approved drug for adults whose AD has not improved with previous treatment. 

 

Study Details

The SWITCH-UP Study is evaluating the safety and efficacy of an approved drug compared to another approved drug in participants with atopic dermatitis (AD). The research study will involve 9 study visits and 4 phone calls over the course of up to 9 months. There is no placebo in this research study - participants will always be on an active treatment that will be adjusted or changed depending on their clinical response. Visit The SWITCH-UP Study | Atopic Dermatitis Clinical Research Study online or contact the study team to learn more.

Compensation: $675
Duration: 32 Weeks
Visits: 9

 

Atopic Dermatitis (Eczema)

Males and Females, Ages 12+.  Qualifying patients will have moderate to severe atopic dermatitis (eczema) diagnosed at least 6 months ago. 

AD is a chronic, relapsing inflammatory skin disease that significantly burdens the patient’s quality of life. Lebrikizumab is a systemic, novel, subcutaneously injected IgG4 monoclonal antibody selectively targeting Interleukin-13 with high binding affinity and slow off-rate, as demonstrated by efficacy and safety in patients with moderate-to-severe AD in clinical studies.

 

Study Details

This is an observational study that seeks to understand the effects of lebrikizumab therapy on the treatment of pediatric and adult participants diagnosed with moderate-to-severe Atopic Dermatitis (AD). The research study will involve 8 study visits over the course of 24 months. Since this is an observational study, visits will align with routine care and subjects will only be required to fill out surveys and perform assessments during their visits.

Compensation: $672
Duration: 24 Weeks
Visits: 8

 

Coming Soon! Research Studies at Denver, Colorado

Cara Mia Dermatology 
3540 S Poplar St, Ste 300
Denver, CO 80237

Submit Your Interest

 

In the News

In the past, our clinical study results indicated that more than one million skin cancers went undiagnosed in 2020 as a result of COVID-19 concerns, and that total-body skin cancer exams are the most effective way to find skin cancers were published nationally in the January 19, 2021 edition of the Journal of the American Academy of Dermatology (JAAD) and Journal of Clinical Oncology®, an American Society of Clinical Oncology (ASCO) Journal.

 

About Us

What We Do, Our Mission, and Research Investigators

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Reasons to Partner With Us on Clinical Trials

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Locations

Advanced Dermatology and
Cosmetic Surgery
1650 Skylyn Dr, Ste 402
Spartanburg, SC 29307

Grekin Skin Institute
Part of Advanced Dermatology and Cosmetic Surgery
13450 E. 12 Mile Rd.
Warren, Michigan 48088

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